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Homovanillyl alcohol

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Catalog No. TN1742Cas No. 2380-78-1

Homovanillyl alcohol, a biological metabolite of Hydroxytyrosol, is a phenolic compound found in virgin olive oil (VOO) and wine. It exhibits high scavenging activities, protects red blood cells from hemolysis in a dose-dependent manner, and has a protective effect on cardiovascular disease and total mortality.

Homovanillyl alcohol

Homovanillyl alcohol

🥰Excellent
Purity: 99.74%
Catalog No. TN1742Cas No. 2380-78-1
Homovanillyl alcohol, a biological metabolite of Hydroxytyrosol, is a phenolic compound found in virgin olive oil (VOO) and wine. It exhibits high scavenging activities, protects red blood cells from hemolysis in a dose-dependent manner, and has a protective effect on cardiovascular disease and total mortality.
Pack SizePriceAvailabilityQuantity
50 mg$30In Stock
100 mg$39In Stock
200 mg$55In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.74%
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Product Introduction

Bioactivity
Description
Homovanillyl alcohol, a biological metabolite of Hydroxytyrosol, is a phenolic compound found in virgin olive oil (VOO) and wine. It exhibits high scavenging activities, protects red blood cells from hemolysis in a dose-dependent manner, and has a protective effect on cardiovascular disease and total mortality.
In vitro
Structurally related compounds have been assayed for their ability to reduce homocysteine-induced monocyte adhesion as well as the cell surface expression of intercellular adhesion molecule-1 (ICAM-1) in EA.hy.926 cells. As well-known, among the selected phenolic compounds, hydroxytyrosol, Homovanillyl alcohol, and the hydroxycinnamic acid derivatives caffeic and ferulic acid display high scavenging activities, while tyrosol and p-coumaric acid are poorly active. All of the tested compounds, approaching potential in vivo concentrations, significantly reduce homocysteine-induced cell adhesion and ICAM-1 expression.
Chemical Properties
Molecular Weight168.19
FormulaC9H12O3
Cas No.2380-78-1
SmilesCOC1=C(O)C=CC(CCO)=C1
Relative Density.1.182 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (148.64 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.9457 mL29.7283 mL59.4566 mL297.2828 mL
5 mM1.1891 mL5.9457 mL11.8913 mL59.4566 mL
10 mM0.5946 mL2.9728 mL5.9457 mL29.7283 mL
20 mM0.2973 mL1.4864 mL2.9728 mL14.8641 mL
50 mM0.1189 mL0.5946 mL1.1891 mL5.9457 mL
100 mM0.0595 mL0.2973 mL0.5946 mL2.9728 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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