Shopping Cart
- Remove All
Your shopping cart is currently empty
Imbricatolic acid
Catalog No. TN4250Cas No. 6832-60-6
Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells.
Imbricatolic acid
Catalog No. TN4250Cas No. 6832-60-6
Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $620 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $630 | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Imbricatolic acid"
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
- $33.6
- $42
Size
QTY
CitedIndole-3-carbinol
Indole-3-Methanol, I3C, 3-Indolemethanol
T2947700-06-1
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
- $29
Size
QTY
XI-006
NSC 207895
T661058131-57-0
XI-006 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
- $51
Size
QTY
RITA Cited
RITA (NSC 652287), NSC 652287
T1798213261-59-7
RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction.
- $30
Size
QTY
CitedP53R3
T41068922150-12-7In house
P53R3 is a potent reactivator of p53, effectively restoring sequence-specific DNA binding to several p53 hot spot mutants, namely p53 R175H, p53 R248W, and p53 R273H. This compound exhibits p53-dependent antiproliferative effects with significantly higher specificity compared to PRIMA-1 and promotes the recruitment of both wild-type p53 and p53 M237I to various target gene promoters. Additionally, P53R3 markedly increases the mRNA, total protein, and cell surface expression of death receptor 5 (DR5), demonstrating its utility in cancer research.
- $68
Size
QTY
DPBQ
ZINC1620467, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione
T110927029-89-2In house
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
- $107
Size
QTY
BAY 1892005
T777682036352-13-1
BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 protein
- $93
Size
QTY
Roslin 2 bromide
Roslin-2, Roslin2, Benzylhexamethylenetetramine bromide
T2473029574-21-8In house
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5, exhibiting anticancer effects.
- $44
Size
QTY
CT-1
CT 1
T270931983924-33-9In house
CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
- $117
Size
QTY
Pifithrin-μ
PFTμ, NSC 303580, 2-Phenylethynesulfonamide
T621064984-31-2
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
- $39
Size
QTY
Magnolol Cited
NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol
T3000528-43-8
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
- $39
Size
QTY
CitedMMRi64
T28078430458-66-5
MMRi64 is a specific inhibitor of Mdm2-MdmX E3 ligase activity.MMRi64 potently induces p53 accumulation and apoptosis in the p53 pathway in leukemia/lymphoma cells, disrupts Mdm2-MdmX interactions, and downregulates Mdm2 and MdmX in leukemia cells.MMRi64 MMRi64 can be used in cancer research.
- $51
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells. |
| Molecular Weight | 322.48 |
| Formula | C20H34O3 |
| Cas No. | 6832-60-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Imbricatolic acid | purchase Imbricatolic acid | Imbricatolic acid cost | order Imbricatolic acid | Imbricatolic acid chemical structure | Imbricatolic acid formula | Imbricatolic acid molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.