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IRAK4-IN-8

🥰Excellent
TargetMol
Catalog No. T63388Cas No. 2033070-97-0

IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor used to study diseases related to cancer and inflammation.

IRAK4-IN-8

IRAK4-IN-8

🥰Excellent
TargetMol
Purity: 99.39%
Catalog No. T63388Cas No. 2033070-97-0
IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor used to study diseases related to cancer and inflammation.
Pack SizePriceAvailabilityQuantity
1 mg$868In Stock
2 mg$1,190In Stock
5 mg$1,770In Stock
10 mg$2,390In Stock
25 mg$3,550In Stock
50 mg$4,780In Stock
100 mg$6,470In Stock
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Purity:99.39%
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Product Introduction

Bioactivity
Description
IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor used to study diseases related to cancer and inflammation.
Chemical Properties
Molecular Weight499.54
FormulaC23H23F2N7O2S
Cas No.2033070-97-0
SmilesN(C(=O)C=1N=C(SC1)C=2C=NNC2)C=3C(=NN(C3)[C@@H]4CC[C@H](OCC)CC4)C5=C(F)C=CC(F)=N5
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (45.26 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0018 mL10.0092 mL20.0184 mL100.0921 mL
5 mM0.4004 mL2.0018 mL4.0037 mL20.0184 mL
10 mM0.2002 mL1.0009 mL2.0018 mL10.0092 mL
20 mM0.1001 mL0.5005 mL1.0009 mL5.0046 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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