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JH-X-119-01
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JH-X-119-01
Catalog No. T9203Cas No. 2227368-54-7
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $60 | In Stock | |
| 2 mg | $88 | In Stock | |
| 5 mg | $147 | In Stock | |
| 10 mg | $222 | In Stock | |
| 25 mg | $396 | In Stock | |
| 50 mg | $592 | In Stock | |
| 100 mg | $822 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $162 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1. |
| In vitro | JH-X-119-01 exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88.?Cotreatment of JH-X-119-01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems. |
| Molecular Weight | 452.46 |
| Formula | C25H20N6O3 |
| Cas No. | 2227368-54-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||
| Solubility Information | DMSO: 12 mg/ml (26.52 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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