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Irloxacin

Irloxacin
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Irloxacin

Catalog No. T9680Cas No. 91524-15-1
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria.
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Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$247In Stock
10 mg$397In Stock
25 mg$663In Stock
50 mg$945In Stock
100 mg$1,280In Stock
500 mg$2,570In Stock
1 mL x 10 mM (in DMSO)$272In Stock
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Product Introduction

Bioactivity
Description
Irloxacin is a new quinolone derivative, and shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria.
In vitro
We have compared the in vitro activity of irloxacin against mycobacteria (20 M. tuberculosis, 17 M. avium, 5 Mycobacterium bovis, 5 Mycobacterium chelonae, 5 Mycobacterium fortuitum and 1 Mycobacterium gadium) using the Bactec at pH 6.8 and 5.0, with other quinolones (ofloxacin, ciprofloxacin, pefloxacin and 27753 RP). All quinolones tested showed good activity against mycobacteria at pH 6.8 and 5.0. Irloxacin at pH 5.0 had a greater activity against M. avium[2].
Chemical Properties
Molecular Weight300.28
FormulaC16H13FN2O3
Cas No.91524-15-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 25 mg/mL (83.25 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3302 mL16.6511 mL33.3023 mL166.5113 mL
5 mM0.6660 mL3.3302 mL6.6605 mL33.3023 mL
10 mM0.3330 mL1.6651 mL3.3302 mL16.6511 mL
20 mM0.1665 mL0.8326 mL1.6651 mL8.3256 mL
50 mM0.0666 mL0.3330 mL0.6660 mL3.3302 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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