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Karacolinem is a natural product, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 60 € | In Stock | |
5 mg | 154 € | In Stock | |
10 mg | 249 € | In Stock | |
25 mg | 423 € | In Stock | |
50 mg | 612 € | In Stock | |
1 mL x 10 mM (in DMSO) | 170 € | In Stock |
Description | Karacolinem is a natural product, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway. |
In vitro | From the ethanol extract, six feeding deterrents were isolated by bioassay-guided fractionation. The compounds were identified as chasmanine, crassicauline A, Karacoline, sachaconitine, talatisamine, and yunaconitine from their spectroscopic data. Chasmanine, talatisamine, Karacoline, and sachaconitine exhibited feeding deterrent activity against T. castaneum adults, with EC(50) values of 297.0, 342.8, 395.3, and 427.8 ppm, respectively. Yunaconitine and crassicauline A also possessed feeding deterrent activity against T. castaneum adults, with EC(50) values of 653.4 and 1134.5 ppm, respectively. |
Molecular Weight | 377.52 |
Formula | C22H35NO4 |
Cas No. | 39089-30-0 |
Smiles | [H][C@]12C[C@]3([H])[C@]([H])([C@H]1O)[C@](O)(C[C@@H]2OC)C1C[C@@]2([H])C33C1N(CC)C[C@]2(C)CC[C@@H]3O |
Relative Density. | 1.3g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/ml (79.47 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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