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KKII5
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Purity:97.44%
KKII5
Catalog No. T77288Cas No. 6381-55-1
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $36 | In Stock | |
| 5 mg | $85 | In Stock | |
| 10 mg | $126 | In Stock | |
| 25 mg | $213 | In Stock | |
| 50 mg | $347 | In Stock | |
| 100 mg | $580 | In Stock | |
| 500 mg | $1,260 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $235 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. |
| Targets&IC50 | LOX1:19 μM |
| In vitro | KKII5 (100 μM) has a significant inhibitory effect on lipid peroxidation, with an inhibition rate of 98%.[1] KKII5 interacts with HIS499 of the cavity by forming a π-π stacking interaction between the benzene ring of the molecule and the imidazole ring of HIS499.[1] |
| Molecular Weight | 266.36 |
| Formula | C16H14N2S |
| Cas No. | 6381-55-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (206.49 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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