Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $44 | In Stock | |
5 mg | $97 | In Stock | |
10 mg | $168 | In Stock | |
25 mg | $319 | In Stock | |
50 mg | $549 | In Stock | |
100 mg | $796 | In Stock |
Description | KKL-10, a ribosome rescue inhibitor, has broad-spectrum antimicrobial activity against bacteria. |
In vitro | KKL-10 shows markedly antimicrobial activity against both fully and attenuated virulent strains of F. tularensis. The MIC against F. tularensis strain Schu S4 and LVS are 0.48 and 0.12 μg/mL, respectively. KKL-10 inhibits the intracellular growth of F. tularensis during all stages of infection. KKL-10 cannot affect macrophage function or viability. KKL-10 (17.5 μg/mL) produces cytotoxic effects of less than 5%. The combination of IFN-γ stimulation and KKL-10 can reduce the bacterial load by >99.9%. KKL-10 also inhibits the growth of F. tularensis inside eukaryotic cells and exhibits no toxicity to HepG2 cells. |
Alias | KKL 10 |
Molecular Weight | 364.22 |
Formula | C14H10BrN3O2S |
Cas No. | 952849-76-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 6.8 mg/mL (18.67 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.