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L-750,667 Trihydrochloride
🥰Excellent
Catalog No. T27777Cas No. 1021868-80-3
Alias L-750667 triHydrochloride, L750,667 Trihydrochloride
L-750,667 Trihydrochloride is a selective D4 dopamine receptor antagonist with high potency (Ki = 0.51 nM). By reversing the dopamine-induced inhibition of cAMP (cyclic adenosine monophosphate) accumulation, L-750667 trihydrochloride can be used to study D4 receptors in the central nervous system.
L-750,667 Trihydrochloride
🥰Excellent
Catalog No. T27777Alias L-750667 triHydrochloride, L750,667 TrihydrochlorideCas No. 1021868-80-3
L-750,667 Trihydrochloride is a selective D4 dopamine receptor antagonist with high potency (Ki = 0.51 nM). By reversing the dopamine-induced inhibition of cAMP (cyclic adenosine monophosphate) accumulation, L-750667 trihydrochloride can be used to study D4 receptors in the central nervous system.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $293 | In Stock | |
| 5 mg | $722 | In Stock | |
| 10 mg | $987 | In Stock | |
| 25 mg | $1,520 | In Stock | |
| 50 mg | $1,980 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | L-750,667 Trihydrochloride is a selective D4 dopamine receptor antagonist with high potency (Ki = 0.51 nM). By reversing the dopamine-induced inhibition of cAMP (cyclic adenosine monophosphate) accumulation, L-750667 trihydrochloride can be used to study D4 receptors in the central nervous system. |
| Targets&IC50 | D4 Receptor:0.51 nM (Ki), D4 Receptor:0.16 nM (Kd) |
| Alias | L-750667 triHydrochloride, L750,667 Trihydrochloride |
| Molecular Weight | 527.66 |
| Formula | C18H22Cl3IN4 |
| Cas No. | 1021868-80-3 |
| Smiles | IC1=CC=C(N2CCN(CC2)CC3=CNC4=C3C=CC=N4)C=C1.Cl.Cl.Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 5 mg/mL (9.48 mM), Sonication is recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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