Shopping Cart
- Remove All
- Your shopping cart is currently empty
Leptomerine is an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae). Leptomerine shows as anticholinesterasic activity and can be used in Alzheimer Disease studies.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $82 | In Stock | |
5 mg | $166 | In Stock | |
10 mg | $280 | In Stock | |
25 mg | $460 | In Stock | |
50 mg | $642 | In Stock | |
100 mg | $870 | In Stock | |
200 mg | $1,170 | In Stock | |
1 mL x 10 mM (in DMSO) | $153 | In Stock |
Description | Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity. |
Targets&IC50 | AChE:2.5 mM |
In vitro | Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, Leptomerine, kokusaginine, skimmianine, maculine and flindersiamine. All isolated compounds were tested for acetyl cholinesterase inhibition, in vitro and displayed anticholinesterasic activity. The alkaloid Leptomerine showed the highest activity (IC50 = 2.5 mM), similar to that of the reference compound galanthamine (IC50 = 1.7 mM). |
Molecular Weight | 201.26 |
Formula | C13H15NO |
Cas No. | 22048-97-1 |
Smiles | CN1C=2C(C(=O)C=C1CCC)=CC=CC2 |
Relative Density. | 1.063 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 9 mg/mL (44.72 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.