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Liranaftate

Catalog No. T1497Cas No. 88678-31-3
Alias Piritetrate, M-732

Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.

Liranaftate

Liranaftate

Purity: 99.92%
Catalog No. T1497Alias Piritetrate, M-732Cas No. 88678-31-3
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.
Pack SizePriceAvailabilityQuantity
5 mg$50In Stock
10 mg$79In Stock
25 mg$167In Stock
50 mg$305In Stock
100 mg$459In Stock
200 mg$596In Stock
1 mL x 10 mM (in DMSO)$81In Stock
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Purity:99.92%
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Product Introduction

Bioactivity
Description
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.
AliasPiritetrate, M-732
Chemical Properties
Molecular Weight328.43
FormulaC18H20N2O2S
Cas No.88678-31-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 9 mg/mL (27.4 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0448 mL15.2239 mL30.4479 mL152.2394 mL
5 mM0.6090 mL3.0448 mL6.0896 mL30.4479 mL
10 mM0.3045 mL1.5224 mL3.0448 mL15.2239 mL
20 mM0.1522 mL0.7612 mL1.5224 mL7.6120 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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