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LY377604
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LY377604
Catalog No. T15819Cas No. 204592-94-9
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $127 | In Stock | |
| 5 mg | $318 | In Stock | |
| 10 mg | $472 | In Stock | |
| 25 mg | $773 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity. |
| In vitro | LY377604 is a β1- and β2-adrenergic receptor antagonist as well as a β3-adrenergic receptor agonist, causing a maximal increase in cyclic adenosine monophosphate (cAMP) levels with an EC50 of 2.4 nM[1]. |
| In vivo | LY377604 administered orally at 10mg/kg increases diet-induced obesity in male Long-Evans rats by enhancing calorie expenditure[1]. |
| Molecular Weight | 524.61 |
| Formula | C31H32N4O4 |
| Cas No. | 204592-94-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (152.49 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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