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Meglutol

🥰Excellent
Catalog No. T1664Cas No. 503-49-1
Alias Dicrotalic acid, 3-Hydroxy-3-methylglutaric acid

Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethyl glutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate-limiting enzyme in the biosynthesis of cholesterol.

Meglutol

Meglutol

🥰Excellent
Purity: 99.94%
Catalog No. T1664Alias Dicrotalic acid, 3-Hydroxy-3-methylglutaric acidCas No. 503-49-1
Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethyl glutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate-limiting enzyme in the biosynthesis of cholesterol.
Pack SizePriceAvailabilityQuantity
50 mg$45In Stock
100 mg$74In Stock
1 mL x 10 mM (in DMSO)$48In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethyl glutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate-limiting enzyme in the biosynthesis of cholesterol.
AliasDicrotalic acid, 3-Hydroxy-3-methylglutaric acid
Chemical Properties
Molecular Weight162.14
FormulaC6H10O5
Cas No.503-49-1
SmilesCC(O)(CC(O)=O)CC(O)=O
Relative Density.1.417 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 100 mg/mL (616.7 mM), Sonication is recommended.
DMSO: 65 mg/mL (400.89 mM)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM6.1675 mL30.8375 mL61.6751 mL308.3755 mL
5 mM1.2335 mL6.1675 mL12.3350 mL61.6751 mL
10 mM0.6168 mL3.0838 mL6.1675 mL30.8375 mL
20 mM0.3084 mL1.5419 mL3.0838 mL15.4188 mL
50 mM0.1234 mL0.6168 mL1.2335 mL6.1675 mL
100 mM0.0617 mL0.3084 mL0.6168 mL3.0838 mL

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