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MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein ubiquitination and accelerate mitophagy.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $36 | In Stock | |
5 mg | $89 | In Stock | |
10 mg | $147 | In Stock | |
25 mg | $297 | In Stock | |
50 mg | $478 | In Stock | |
100 mg | $689 | In Stock | |
500 mg | $1,530 | In Stock | |
1 mL x 10 mM (in DMSO) | $123 | In Stock |
Description | MF-094 is a selective USP30 inhibitor with IC50 of 0.12 μM. MF-094 can increase protein ubiquitination and accelerate mitophagy. |
Targets&IC50 | USP30:120 nM |
In vitro | In hypoxic trophoblast cells supplemented with MF-094, GSH and SOD levels increased, while MDA levels decreased. [2] |
In vivo | Subcutaneous injection of MF-094 can promote the ubiquitination level of FUNDC1. MF-094 can significantly reduce the increase in systolic blood pressure and urine protein in PE mice. [2] |
Molecular Weight | 535.7 |
Formula | C30H37N3O4S |
Cas No. | 2241025-68-1 |
Smiles | CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCCCC3)cccc12 |
Relative Density. | 1.229 g/cm3 (Predicted) |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 115 mg/mL (214.67 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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