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MHP 133

Catalog No. T13772Cas No. 147340-43-0

MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).

MHP 133

MHP 133

Catalog No. T13772Cas No. 147340-43-0
MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).
Targets&IC50
AChE:ki:69 μM
In vitro
MHP-133 exhibits this nicotinic-like activity in the cell line. MHP-133 produces a bi-phasic effect on slice survival, particularly in the dentate gyrus and the CA1 regions[1].
In vivo
MHP-133 (50, 100, or 200 μg/kg, i.p.) enhances acquisition of the task and increases task accuracy In rats, elicits significant improvements in task accuracies during sessions initiated 10 min after dosing[1].
Chemical Properties
Molecular Weight377.83
FormulaC17H20ClN5O3
Cas No.147340-43-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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