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Mirodenafil dihydrochloride
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Catalog No. TQ0126Cas No. 862189-96-6
Alias SK-3530 dihydrochloride
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
Mirodenafil dihydrochloride
😃Good
Purity: 99.64%
Catalog No. TQ0126Alias SK-3530 dihydrochlorideCas No. 862189-96-6
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $43 | In Stock | |
| 25 mg | $81 | In Stock | |
| 50 mg | $133 | In Stock | |
| 100 mg | $213 | In Stock | |
| 500 mg | $495 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $35 | In Stock |
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Purity:99.64%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. |
| In vivo | Mirodenafil, in doses of 50 or 100 mg, significantly improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The pharmacokinetics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2]. |
| Alias | SK-3530 dihydrochloride |
| Molecular Weight | 604.59 |
| Formula | C26H39Cl2N5O5S |
| Cas No. | 862189-96-6 |
| Smiles | Cl.Cl.CCCOc1ccc(cc1-c1nc2c(CCC)cn(CC)c2c(=O)[nH]1)S(=O)(=O)N1CCN(CCO)CC1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (82.7 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords
β-cateninWntsystemic sclerosisSK-3530 DihydrochlorideSK3530 DihydrochlorideSK-3530SK3530SK 3530 DihydrochlorideSK 3530SH-SY5YPhosphodiesterase (PDE)phosphodiesterasePDE5NIH3T3MRC-5 cellsMirodenafil DihydrochlorideMirodenafil dihydrochlorideMirodenafilInhibitorinhibitHT-22 cellsGlucocorticoid Receptorfibrosiserectile dysfunctionBeta cateninApoptosisAlzheimer’s disease
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