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ML115

🥰Excellent
Catalog No. T35544Cas No. 912798-42-6

ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.

ML115

ML115

🥰Excellent
Purity: 99.35%
Catalog No. T35544Cas No. 912798-42-6
ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
Pack SizePriceAvailabilityQuantity
1 mg$96In Stock
5 mg$239In Stock
10 mg$378In Stock
25 mg$663In Stock
50 mg$928In Stock
100 mg$1,250In Stock
200 mg$1,680In Stock
500 mg$2,480In Stock
1 mL x 10 mM (in DMSO)$265In Stock
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Purity:99.35%
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Product Introduction

Bioactivity
Description
ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.
Targets&IC50
STAT3:2.0 nM
Chemical Properties
Molecular Weight322.74
FormulaC15H15ClN2O4
Cas No.912798-42-6
SmilesCOc1cc(NC(=O)c2cc(on2)C2CC2)c(OC)cc1Cl
Relative Density.1.389 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 25 mg/mL
DMSO: 12.5 mg/mL (38.73 mM)
Ethanol: 0.1 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0985 mL15.4923 mL30.9847 mL154.9235 mL
5 mM0.6197 mL3.0985 mL6.1969 mL30.9847 mL
10 mM0.3098 mL1.5492 mL3.0985 mL15.4923 mL
20 mM0.1549 mL0.7746 mL1.5492 mL7.7462 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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