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ML213

🥰Excellent
Catalog No. T4030Cas No. 489402-47-3
Alias CID-3111211

ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

ML213

ML213

🥰Excellent
Purity: 99.74%
Catalog No. T4030Alias CID-3111211Cas No. 489402-47-3
ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
Pack SizePriceAvailabilityQuantity
2 mg$34In Stock
5 mg$52In Stock
10 mg$79In Stock
25 mg$158In Stock
50 mg$239In Stock
100 mg$359In Stock
1 mL x 10 mM (in DMSO)$57In Stock
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Purity:99.74%
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Product Introduction

Bioactivity
Description
ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
Targets&IC50
Kv7.4 channel:510 nM(EC50), Kv7.2 channel:230nM (EC50)
AliasCID-3111211
Chemical Properties
Molecular Weight257.37
FormulaC17H23NO
Cas No.489402-47-3
SmilesCc1cc(C)c(NC(=O)C2CC3CCC2C3)c(C)c1
Relative Density.1.106 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 9 mg/mL (34.97 mM), Sonication is recommended.
Ethanol: 30 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8855 mL19.4273 mL38.8546 mL194.2728 mL
5 mM0.7771 mL3.8855 mL7.7709 mL38.8546 mL
10 mM0.3885 mL1.9427 mL3.8855 mL19.4273 mL
20 mM0.1943 mL0.9714 mL1.9427 mL9.7136 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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