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MY-1B
🥰Excellent
Catalog No. T85335Cas No. 2929308-79-0
Alias MY1B
MY-1B is a nitrogen-containing substituted butenamide stereoprobe, capable of blocking stereoselective enrichment of NSUN2, specifically binding to NSUN2 at C271.
MY-1B
🥰Excellent
Purity: 100%
Catalog No. T85335Alias MY1BCas No. 2929308-79-0
MY-1B is a nitrogen-containing substituted butenamide stereoprobe, capable of blocking stereoselective enrichment of NSUN2, specifically binding to NSUN2 at C271.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $136 | In Stock | |
| 5 mg | $338 | In Stock | |
| 10 mg | $538 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,490 | In Stock | |
| 100 mg | $1,980 | In Stock | |
| 200 mg | $2,670 | In Stock |
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Purity:100%
ee:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MY-1B is a nitrogen-containing substituted butenamide stereoprobe, capable of blocking stereoselective enrichment of NSUN2, specifically binding to NSUN2 at C271. |
| Targets&IC50 | NSUN2:1.3 μM |
| In vitro | Methods: The binding of NSUN2_C271 was observed in the human prostate cancer cell line 22Rv1 treated with 5 or 20 μM MY-1B (3 hours). Results: Almost complete binding of NSUN2_C271 (>90%) was observed in the human prostate cancer cell line 22Rv1. [1] The Kinact/Ki value of MY-1B (2.5-20 µM) against recombinant NSUN2 methyltransferase activity at different pre-incubation times and concentrations was 67±15 M. [1] |
| Alias | MY1B |
| Molecular Weight | 436.3 |
| Formula | C22H18BrN3O2 |
| Cas No. | 2929308-79-0 |
| Smiles | C(NC=1C2=C(C=CC1)C=CC=N2)(=O)[C@H]3[C@H](CN3C(C=C)=O)C4=CC=C(Br)C=C4 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80.00 mg/mL (183.36 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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