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TFMB-(S)-2-HG

TFMB-(S)-2-HG
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML).
Catalog No. T24871Cas No. 1445703-64-9
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Purity:98.88%
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TFMB-(S)-2-HG

Catalog No. T24871Cas No. 1445703-64-9
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$30In Stock
5 mg$48In Stock
10 mg$76In Stock
25 mg$157In Stock
50 mg$253In Stock
100 mg$376In Stock
500 mg$793In Stock
1 mL x 10 mM (in DMSO)$47In Stock
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Product Introduction

Bioactivity
Description
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML).
AliasTFMB(S)2HG, TFMB-S-2-HG, TFMB (S) 2 HG, TFMB S 2 HG
Chemical Properties
Molecular Weight288.22
FormulaC13H11F3O4
Cas No.1445703-64-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (208.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4696 mL17.3479 mL34.6957 mL173.4786 mL
5 mM0.6939 mL3.4696 mL6.9391 mL34.6957 mL
10 mM0.3470 mL1.7348 mL3.4696 mL17.3479 mL
20 mM0.1735 mL0.8674 mL1.7348 mL8.6739 mL
50 mM0.0694 mL0.3470 mL0.6939 mL3.4696 mL
100 mM0.0347 mL0.1735 mL0.3470 mL1.7348 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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