Shopping Cart
- Remove All
Your shopping cart is currently empty
TFMB-(S)-2-HG
🥰Excellent
Catalog No. T24871Cas No. 1445703-64-9
Alias TFMB-S-2-HG, TFMB(S)2HG, TFMB S 2 HG, TFMB (S) 2 HG
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML).
TFMB-(S)-2-HG
🥰Excellent
Purity: 98.88%
Catalog No. T24871Alias TFMB-S-2-HG, TFMB(S)2HG, TFMB S 2 HG, TFMB (S) 2 HGCas No. 1445703-64-9
TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $30 | In Stock | |
| 5 mg | $48 | In Stock | |
| 10 mg | $76 | In Stock | |
| 25 mg | $157 | In Stock | |
| 50 mg | $253 | In Stock | |
| 100 mg | $376 | In Stock | |
| 500 mg | $793 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $47 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "TFMB-(S)-2-HG"
γ-Oryzanol
Oliver, Gammariza, Gamma-Oryzanol
T360611042-64-1
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently been researched for its ability to slow the progress of melanin pigmentation by intercepting the ultraviolet rays at the skin's surface and hindering their transmission.
- $41
Size
QTY
Levetiracetam
UCB L059, SIB-S1
T0192102767-28-2
Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset seizures. Levetiracetam has been linked to rare instances of serum aminotransferase and alkaline phosphatase elevations during treatment and to rare cases of clinically apparent drug induced liver disease.
- $50
Size
QTY
5-Azacytidine
Cited
NSC 102816, Mylosar, Ladakamycin, Azacitidine, 5-AzaC
T1339320-67-2
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autophagy and has antitumor activity.
- $33
Size
QTY
CitedProcainamide hydrochloride
Pronestyl, Procapan, Procanbid, Procainamide HCl
T0018614-39-1
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to and blocks activated (open) voltage-gated sodium channels, thereby blocks the influx of sodium ions into the cell, which leads to an increase in threshold for excitation and inhibit depolarization during phase 0 of the action potential.
- $41
Size
QTY
Zebularine
NSC309132, 4-Deoxyuridine
T21693690-10-6
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2 μM, in a cell-free assay).
- $38
Size
QTY
SW155246
T8967420092-79-1
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
- $43
Size
QTY
5-Methyl-2'-deoxycytidine
5-Methyldeoxycytidine, 5MedCyd
T7457838-07-3
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.
- $35
Size
QTY
6-Thioguanine Cited
Thioguanine, 6-TG, 2-Amino-6-purinethiol, 2-Amino-6-mercaptopurine
T3089154-42-7
6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
- $40
Size
QTY
CitedGSK-3484862
T114692170136-65-7In house
GSK-3484862 is a non-covalent Dnmt1 inhibitor that induces DNA hypomethylation, offering potential therapeutic benefits against cancer.
- $43
Size
QTY
Hinokitiol
β-thujaplicin, 4-Isopropyltropolone
T3717499-44-5
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent. Also, Hinokitiol modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells.
- $31
Size
QTY
Dihydro-5-azacytidine FA
NSC 264880 FA, Dihydro-5-azacytidine FA（62488-57-7 Free base）, DHAC FA
T40713LIn house
Dihydro-5-azacytidine FA (DHAC) is a pyrimidine analog that has antitumor activity, inhibits cell growth, inhibits DNA methylation, and may be used in the study of malignant mesothelioma.
- $195
Size
QTY
NSC 127716, Deoxycytidine, Dacogen, 5-Aza-2'-deoxycytidine
T15082353-33-5
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.
- $24
- $30
Size
QTY
CitedSelect Batch
Purity:98.88%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase. Additionally, it significantly inhibits the EglN prolyl hydroxylases. With its unique properties, TFMB-(S)-2-HG holds great promise for advancing research in the field of acute myeloid leukemia (AML). |
| Alias | TFMB-S-2-HG, TFMB(S)2HG, TFMB S 2 HG, TFMB (S) 2 HG |
| Molecular Weight | 288.22 |
| Formula | C13H11F3O4 |
| Cas No. | 1445703-64-9 |
| Smiles | FC(F)(F)c1cccc(COC(=O)[C@@H]2CCC(=O)O2)c1 |
| Relative Density. | 1.385 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (208.17 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy TFMB-(S)-2-HG | purchase TFMB-(S)-2-HG | TFMB-(S)-2-HG cost | order TFMB-(S)-2-HG | TFMB-(S)-2-HG chemical structure | TFMB-(S)-2-HG formula | TFMB-(S)-2-HG molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.