Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

SW155246

🥰Excellent
Catalog No. T8967Cas No. 420092-79-1

SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.

SW155246

SW155246

🥰Excellent
Purity: 97.79%
Catalog No. T8967Cas No. 420092-79-1
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
Pack SizePriceAvailabilityQuantity
5 mg$43In Stock
10 mg$68In Stock
25 mg$142In Stock
50 mg$226In Stock
100 mg$358In Stock
500 mg$768In Stock
1 mL x 10 mM (in DMSO)$42In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "SW155246"

Select Batch
Purity:97.79%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
Targets&IC50
DNMT1:1.2 μM
Chemical Properties
Molecular Weight378.79
FormulaC16H11ClN2O5S
Cas No.420092-79-1
SmilesOc1ccc(NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c2ccccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (132 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6400 mL13.1999 mL26.3999 mL131.9993 mL
5 mM0.5280 mL2.6400 mL5.2800 mL26.3999 mL
10 mM0.2640 mL1.3200 mL2.6400 mL13.1999 mL
20 mM0.1320 mL0.6600 mL1.3200 mL6.6000 mL
50 mM0.0528 mL0.2640 mL0.5280 mL2.6400 mL
100 mM0.0264 mL0.1320 mL0.2640 mL1.3200 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy SW155246 | purchase SW155246 | SW155246 cost | order SW155246 | SW155246 chemical structure | SW155246 formula | SW155246 molecular weight