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Nikethamide

Catalog No. T0048Cas No. 59-26-7
Alias N,N-Diethylnicotinamide, Corvotone, Corvin, Anacardone

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now thought to be of no value for such purposes, and may be dangerous.

Nikethamide

Nikethamide

Purity: 98.75%
Catalog No. T0048Alias N,N-Diethylnicotinamide, Corvotone, Corvin, AnacardoneCas No. 59-26-7
Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now thought to be of no value for such purposes, and may be dangerous.
Pack SizePriceAvailabilityQuantity
500 mg$40In Stock
1 g$50In Stock
5 g$113In Stock
10 g$166In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:98.75%
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Product Introduction

Bioactivity
Description
Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end
AliasN,N-Diethylnicotinamide, Corvotone, Corvin, Anacardone
Chemical Properties
Molecular Weight178.23
FormulaC10H14N2O
Cas No.59-26-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (252.48 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.6107 mL28.0536 mL56.1073 mL280.5364 mL
5 mM1.1221 mL5.6107 mL11.2215 mL56.1073 mL
10 mM0.5611 mL2.8054 mL5.6107 mL28.0536 mL
20 mM0.2805 mL1.4027 mL2.8054 mL14.0268 mL
50 mM0.1122 mL0.5611 mL1.1221 mL5.6107 mL
100 mM0.0561 mL0.2805 mL0.5611 mL2.8054 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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