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NT219

🥰Excellent
Catalog No. T62105Cas No. 1198078-60-2
Alias NT-219

NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.

NT219

NT219

🥰Excellent
Purity: 99.72%
Catalog No. T62105Alias NT-219Cas No. 1198078-60-2
NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.
Pack SizePriceAvailabilityQuantity
1 mg125 €In Stock
5 mg311 €In Stock
10 mg462 €In Stock
25 mg756 €In Stock
50 mg1.035 €In Stock
100 mg1.406 €In Stock
200 mg1.881 €In Stock
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Purity:99.72%
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Product Introduction

Bioactivity
Description
NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3, enhances the aggregation of misfolded prion protein NT219 affects the levels of certain molecular chaperones and inhibits STAT3 phosphorylation NT219 is useful for the study of cancer and neurodegenerative diseases.
AliasNT-219
Chemical Properties
Molecular Weight412.26
FormulaC16H14BrNO5S
Cas No.1198078-60-2
SmilesOc1ccc(\C=C\C(=S)NCc2cc(O)c(O)c(O)c2)c(Br)c1O
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (194.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4257 mL12.1283 mL24.2565 mL121.2827 mL
5 mM0.4851 mL2.4257 mL4.8513 mL24.2565 mL
10 mM0.2426 mL1.2128 mL2.4257 mL12.1283 mL
20 mM0.1213 mL0.6064 mL1.2128 mL6.0641 mL
50 mM0.0485 mL0.2426 mL0.4851 mL2.4257 mL
100 mM0.0243 mL0.1213 mL0.2426 mL1.2128 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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