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ON-013100
🥰Excellent
Catalog No. T16391Cas No. 865783-95-5
ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.
ON-013100
🥰Excellent
Purity: 98.27%
Catalog No. T16391Cas No. 865783-95-5
ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $43 | In Stock | |
| 5 mg | $68 | In Stock | |
| 10 mg | $107 | In Stock | |
| 25 mg | $191 | In Stock | |
| 50 mg | $297 | In Stock | |
| 100 mg | $448 | In Stock | |
| 200 mg | $633 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
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Purity:98.27%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression. |
| In vitro | ON 013100 effectively inhibits the proliferation of various cancer cell lines, including mantle cell lymphoma (MCL; JEKO-1 and MINO), breast (MCF7 and MDA-MB-231), gastric (AGS), and esophageal (OE19, OE33, FLO-1) at nanomolar concentrations (ON 013100 GI50=6.7-11.2 nM). It significantly modifies the cell cycle distribution, notably increasing the population of cells at the G2/M phase, with treatment at just 0.1 μM leading to G2/M phase arrest. Additionally, ON-013100 triggers apoptosis, demonstrating broad-spectrum anti-cancer activity in vitro[2][3]. |
| Molecular Weight | 394.44 |
| Formula | C19H22O7S |
| Cas No. | 865783-95-5 |
| Smiles | COc1cc(OC)c(\C=C\S(=O)(=O)Cc2ccc(OC)c(O)c2)c(OC)c1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 25 mg/mL (63.38 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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