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PCI-27483

🥰Excellent
Catalog No. T3469Cas No. 871266-63-6
Alias PCI27483

PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg, respectively.

PCI-27483

PCI-27483

🥰Excellent
Purity: 98.45%
Catalog No. T3469Alias PCI27483Cas No. 871266-63-6
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg, respectively.
Pack SizePriceAvailabilityQuantity
1 mg$34 In Stock
5 mg$79 In Stock
10 mg$133 In Stock
25 mg$226 In Stock
50 mg$340 In Stock
1 mL x 10 mM (in DMSO)$98 In Stock
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Purity:98.45%
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Product Introduction

Bioactivity
Description
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg, respectively.
AliasPCI27483
Chemical Properties
Molecular Weight596.57
FormulaC26H24N6O9S
Cas No.871266-63-6
SmilesNC(=N)c1ccc2[nH]c(nc2c1)-c1cc(CC(=O)N[C@@H](CC(O)=O)C(O)=O)cc(c1O)-c1cc(ccc1O)S(N)(=O)=O
Relative Density.1.74 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (75.43 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6762 mL8.3812 mL16.7625 mL83.8125 mL
5 mM0.3352 mL1.6762 mL3.3525 mL16.7625 mL
10 mM0.1676 mL0.8381 mL1.6762 mL8.3812 mL
20 mM0.0838 mL0.4191 mL0.8381 mL4.1906 mL
50 mM0.0335 mL0.1676 mL0.3352 mL1.6762 mL

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