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Phleomycin

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Catalog No. T21498Cas No. 11006-33-0

Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.

Phleomycin

Phleomycin

🥰Excellent
Catalog No. T21498Cas No. 11006-33-0
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
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1 mg$30In Stock
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Product Introduction

Bioactivity
Description
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
Chemical Properties
Molecular Weight1268.29
FormulaC48H69N17O20S2
Cas No.11006-33-0
SmilesNC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1
Relative Density.1.3193 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 100 mg/mL (75.39 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.7885 mL3.9423 mL7.8846 mL39.4232 mL
5 mM0.1577 mL0.7885 mL1.5769 mL7.8846 mL
10 mM0.0788 mL0.3942 mL0.7885 mL3.9423 mL
20 mM0.0394 mL0.1971 mL0.3942 mL1.9712 mL
50 mM0.0158 mL0.0788 mL0.1577 mL0.7885 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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