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Podocarpic acid

🥰Excellent
Catalog No. T12514Cas No. 5947-49-9

Podocarpic acid is a natural product and a novel TRPA1 activator.

Podocarpic acid

Podocarpic acid

🥰Excellent
Purity: 99.67%
Catalog No. T12514Cas No. 5947-49-9
Podocarpic acid is a natural product and a novel TRPA1 activator.
Pack SizePriceAvailabilityQuantity
10 mg$59In Stock
25 mg$94In Stock
50 mg$136In Stock
100 mg$198In Stock
1 mL x 10 mM (in DMSO)$61In Stock
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Purity:99.67%
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Product Introduction

Bioactivity
Description
Podocarpic acid is a natural product and a novel TRPA1 activator.
In vitro
Podocarpic acid activates SKN-1 in C. elegans, similar to known Nrf2 activators such as α-lipoic acid (LA)[1].
In vivo
Podocarpic acid and LA alleviate the Podocarpic acidthogenic phenotypes of glod-4 animals by reverting the high endogenous MGO and GO to almost wild-type-like levels[1].
Chemical Properties
Molecular Weight274.35
FormulaC17H22O3
Cas No.5947-49-9
Smiles[H][C@@]12CCc3ccc(O)cc3[C@@]1(C)CCC[C@]2(C)C(O)=O
Relative Density.1.182 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (364.50 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6450 mL18.2249 mL36.4498 mL182.2490 mL
5 mM0.7290 mL3.6450 mL7.2900 mL36.4498 mL
10 mM0.3645 mL1.8225 mL3.6450 mL18.2249 mL
20 mM0.1822 mL0.9112 mL1.8225 mL9.1124 mL
50 mM0.0729 mL0.3645 mL0.7290 mL3.6450 mL
100 mM0.0364 mL0.1822 mL0.3645 mL1.8225 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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