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Podocarpic acid

Podocarpic acid
Podocarpic acid is a natural product and a novel TRPA1 activator.
Catalog No. T12514Cas No. 5947-49-9
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Purity:99.67%
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Podocarpic acid

Catalog No. T12514Cas No. 5947-49-9

Podocarpic acid is a natural product and a novel TRPA1 activator.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
10 mg$35In Stock
25 mg$56In Stock
50 mg$82In Stock
100 mg$119In Stock
200 mg$175In Stock
1 mL x 10 mM (in DMSO)$37In Stock
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Product Introduction

Bioactivity
Description
Podocarpic acid is a natural product and a novel TRPA1 activator.
In vitro
Podocarpic acid activates SKN-1 in C. elegans, similar to known Nrf2 activators such as α-lipoic acid (LA)[1].
In vivo
Podocarpic acid and LA alleviate the Podocarpic acidthogenic phenotypes of glod-4 animals by reverting the high endogenous MGO and GO to almost wild-type-like levels[1].
Chemical Properties
Molecular Weight274.35
FormulaC17H22O3
Cas No.5947-49-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (364.50 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6450 mL18.2249 mL36.4498 mL182.2490 mL
5 mM0.7290 mL3.6450 mL7.2900 mL36.4498 mL
10 mM0.3645 mL1.8225 mL3.6450 mL18.2249 mL
20 mM0.1822 mL0.9112 mL1.8225 mL9.1124 mL
50 mM0.0729 mL0.3645 mL0.7290 mL3.6450 mL
100 mM0.0364 mL0.1822 mL0.3645 mL1.8225 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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