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Pumaprazole
Catalog No. T16682Cas No. 158364-59-1
Alias BY-841
Pumaprazole (BY-841) is an antagonist of a reversible proton pump.
Pumaprazole
Catalog No. T16682Alias BY-841Cas No. 158364-59-1
Pumaprazole (BY-841) is an antagonist of a reversible proton pump.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $84 | In Stock | |
| 5 mg | $198 | In Stock | |
| 10 mg | $328 | In Stock | |
| 25 mg | $668 | In Stock | |
| 50 mg | $1,070 | In Stock | |
| 100 mg | $1,730 | In Stock | |
| 200 mg | $2,330 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $226 | In Stock |
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View MoreInhibitors Related to "Pumaprazole"
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Esomeprazole Sodium
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Pantoprazole sodium
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Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.
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Purity:99.6%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pumaprazole (BY-841) is an antagonist of a reversible proton pump. |
| In vivo | Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1]. |
| Alias | BY-841 |
| Molecular Weight | 338.4 |
| Formula | C19H22N4O2 |
| Cas No. | 158364-59-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/ml (162.53 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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