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Pumaprazole

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Catalog No. T16682Cas No. 158364-59-1
Alias BY-841

Pumaprazole (BY-841) is an antagonist of a reversible proton pump.

Pumaprazole

Pumaprazole

🥰Excellent
Purity: 99.6%
Catalog No. T16682Alias BY-841Cas No. 158364-59-1
Pumaprazole (BY-841) is an antagonist of a reversible proton pump.
Pack SizePriceAvailabilityQuantity
1 mg$84In Stock
5 mg$198In Stock
10 mg$328In Stock
25 mg$668In Stock
50 mg$1,070In Stock
100 mg$1,730In Stock
200 mg$2,330In Stock
1 mL x 10 mM (in DMSO)$226In Stock
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Purity:99.6%
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Product Introduction

Bioactivity
Description
Pumaprazole (BY-841) is an antagonist of a reversible proton pump.
In vivo
Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1].
AliasBY-841
Chemical Properties
Molecular Weight338.4
FormulaC19H22N4O2
Cas No.158364-59-1
SmilesCOC(=O)Nc1cccc(C)c1CNc1cccn2c(C)c(C)nc12
Relative Density.1.21g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (162.53 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9551 mL14.7754 mL29.5508 mL147.7541 mL
5 mM0.5910 mL2.9551 mL5.9102 mL29.5508 mL
10 mM0.2955 mL1.4775 mL2.9551 mL14.7754 mL
20 mM0.1478 mL0.7388 mL1.4775 mL7.3877 mL
50 mM0.0591 mL0.2955 mL0.5910 mL2.9551 mL
100 mM0.0296 mL0.1478 mL0.2955 mL1.4775 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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