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Qc1

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Catalog No. T23209Cas No. 403718-45-6
Alias Qc 1

Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.

Qc1

Qc1

🥰Excellent
Purity: 100%
Catalog No. T23209Alias Qc 1Cas No. 403718-45-6
Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.
Pack SizePriceAvailabilityQuantity
2 mg$35In Stock
5 mg$58In Stock
10 mg$98In Stock
25 mg$173In Stock
50 mg$260In Stock
100 mg$377In Stock
200 mg$536In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.
In vitro
Qc1 prevents threonine dehydrogenase from catabolizing threonine into acetyl-CoA and glycine and blocks the charging of tetrahydrofolate(THF). In ES cells, Qc1 (10 μM) increases autophagic activity[2].
AliasQc 1
Chemical Properties
Molecular Weight455.45
FormulaC23H16F3N3O2S
Cas No.403718-45-6
SmilesFC(F)(F)C1=CC(=CC=C1)N1C(=S)NC2=CC(=CC=C2C1=O)C(=O)NCC1=CC=CC=C1
Relative Density.1.48 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/ml (43.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1956 mL10.9782 mL21.9563 mL109.7815 mL
5 mM0.4391 mL2.1956 mL4.3913 mL21.9563 mL
10 mM0.2196 mL1.0978 mL2.1956 mL10.9782 mL
20 mM0.1098 mL0.5489 mL1.0978 mL5.4891 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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