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R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $31 | In Stock | |
5 mg | $55 | In Stock | |
10 mg | $89 | In Stock | |
25 mg | $169 | In Stock | |
50 mg | $297 | In Stock | |
100 mg | $439 | In Stock | |
1 mL x 10 mM (in DMSO) | $97 | In Stock |
Description | R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef). |
In vitro | IAA-94 has been utilized for its high affinity to modulate chloride channel activity, serving as a tool to investigate the channels' dynamics and functions. This property has also facilitated the isolation and reconstitution of these proteins [1][2]. |
Alias | R(+)-Methylindazone |
Molecular Weight | 357.23 |
Formula | C17H18Cl2O4 |
Cas No. | 54197-31-8 |
Smiles | C[C@@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C1CCCC1 |
Relative Density. | 1.401 g/cm3 (Predicted) |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90 mg/mL (251.9 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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