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R(+)-IAA-94
Catalog No. T12788Cas No. 54197-31-8
Alias R(+)-Methylindazone
R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
R(+)-IAA-94
Catalog No. T12788Alias R(+)-MethylindazoneCas No. 54197-31-8
R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $31 | In Stock | |
| 5 mg | $55 | In Stock | |
| 10 mg | $89 | In Stock | |
| 25 mg | $169 | In Stock | |
| 50 mg | $297 | In Stock | |
| 100 mg | $439 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $97 | In Stock |
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Purity:99.22%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | R(+)-IAA-94 (R(+)-Methylindazone) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-IAA-94 inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef). |
| In vitro | IAA-94 has been utilized for its high affinity to modulate chloride channel activity, serving as a tool to investigate the channels' dynamics and functions. This property has also facilitated the isolation and reconstitution of these proteins [1][2]. |
| Alias | R(+)-Methylindazone |
| Molecular Weight | 357.23 |
| Formula | C17H18Cl2O4 |
| Cas No. | 54197-31-8 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (251.9 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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