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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $34 | In Stock | |
2 mg | $48 | In Stock | |
5 mg | $79 | In Stock | |
10 mg | $133 | In Stock | |
25 mg | $272 | In Stock | |
50 mg | $446 | In Stock | |
100 mg | $658 | In Stock | |
500 mg | $1,380 | In Stock | |
1 mL x 10 mM (in DMSO) | $95 | In Stock |
Description | RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively. |
Targets&IC50 | C-Raf:0.5 nM, B-Raf:1.8 nM |
In vitro | The invention provides compounds (e.g., RAF709) that inhibit Raf kinases, and are accordingly useful for treating certain disorders associated with excessive Raf kinase activity, including cell proliferation disorders such as cancers[1]. |
Molecular Weight | 542.55 |
Formula | C28H29F3N4O4 |
Cas No. | 1628838-42-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 91 mg/mL (167.8 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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