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Refametinib R enantiomer
Catalog No. T12697Cas No. 923032-38-6
Alias Refametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomer
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
Refametinib R enantiomer
Catalog No. T12697Alias Refametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomerCas No. 923032-38-6
Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $85 | In Stock | |
| 5 mg | $210 | In Stock | |
| 10 mg | $310 | In Stock | |
| 25 mg | $586 | In Stock | |
| 50 mg | $780 | In Stock | |
| 100 mg | $1,090 | In Stock | |
| 500 mg | $2,180 | In Stock |
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Purity:99.43%
ee:98.92%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used in cancer research. |
| Targets&IC50 | MEK:2-15 nM （EC50） |
| In vitro | Refametinib R enantiomer is the R enantiomer of Refametinib. It functions as an MEK inhibitor and is used in the treatment of cancer and other hyperproliferative diseases.[1] |
| Alias | Refametinib R enantiomer, RDEA119 R enantiomer, BAY 869766 R enantiomer |
| Molecular Weight | 572.34 |
| Formula | C19H20F3IN2O5S |
| Cas No. | 923032-38-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (96.1 mM)  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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