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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $51 | In Stock | |
2 mg | $72 | In Stock | |
5 mg | $130 | In Stock | |
10 mg | $217 | In Stock | |
25 mg | $363 | In Stock | |
50 mg | $539 | In Stock | |
100 mg | $778 | In Stock | |
1 mL x 10 mM (in DMSO) | $117 | In Stock |
Description | Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches, strongly inhibiting GFP expression with a 50% effective concentration (EC50: 0.3 μM). |
In vitro | Ribocil is a highly specific bioactive synthetic mimic of FMN, which competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB and inhibits bacterial growth. Ribocil-B shows superior microbiological activity as compared to Ribocil-A (minimum inhibitory concentration (MIC) = 1 μg/ml versus MIC ≥ 64 μg/ml), inhibition of riboflavin synthesis (IC50 = 0.13 μM versus IC50 > 26 μM), and binding affinity to the E. coli FMN aptamer (Kd = 6.6 nM versus Kd ≥ 10,000 nM) [1] |
Molecular Weight | 382.48 |
Formula | C19H22N6OS |
Cas No. | 1381289-58-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 24.8 mg/mL (64.84 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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