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Rutaevin

Rutaevin
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Purity:99.99%
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Rutaevin

Catalog No. TN2167Cas No. 33237-37-5
Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$287In Stock
5 mg$691In Stock
10 mg$985In Stock
25 mg$1,490In Stock
50 mg$1,960In Stock
1 mL x 10 mM (in DMSO)$793In Stock
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Product Introduction

Bioactivity
Description
Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent.
In vitro
A new limonoid compound, named evorubodinin (1), was isolated from the dried and nearly ripe fruits of Euodia rutaecarpa (Juss.) Benth. var. bodinieri (Dode) Huang (family Rutaceae), together with two known limonoid compounds, limonin (2) and evolimorutanin (3). The chemical structure of 1 was elucidated by spectroscopic method and single-crystal X-ray diffraction. The inhibitory effects of the isolated compounds 1-3 and the structurally related compounds evodol (4), shihulimonin A1 (5), evodirutaenin (6), 12α±-hydroxyRutaevin (7), and Rutaevin (8) on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages were also assayed[1]
Chemical Properties
Molecular Weight486.51
FormulaC26H30O9
Cas No.33237-37-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (123.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0555 mL10.2773 mL20.5546 mL102.7728 mL
5 mM0.4111 mL2.0555 mL4.1109 mL20.5546 mL
10 mM0.2055 mL1.0277 mL2.0555 mL10.2773 mL
20 mM0.1028 mL0.5139 mL1.0277 mL5.1386 mL
50 mM0.0411 mL0.2055 mL0.4111 mL2.0555 mL
100 mM0.0206 mL0.1028 mL0.2055 mL1.0277 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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