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SJ000063181

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Catalog No. T60644Cas No. 945189-68-4

SJ000063181 is a potent activator of BMP signaling, exhibiting an EC50 of ≤1 μM. It serves as a valuable chemical probe for BMP signaling analysis, owing to its ability to penetrate zebrafish embryos.

SJ000063181

SJ000063181

🥰Excellent
Purity: 99.83%
Catalog No. T60644Cas No. 945189-68-4
SJ000063181 is a potent activator of BMP signaling, exhibiting an EC50 of ≤1 μM. It serves as a valuable chemical probe for BMP signaling analysis, owing to its ability to penetrate zebrafish embryos.
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
5 mg$98In Stock
10 mg$152In Stock
25 mg$297In Stock
50 mg$578In Stock
100 mg$833In Stock
500 mg$1,690In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Purity:99.83%
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Product Introduction

Bioactivity
Description
SJ000063181 is a potent activator of BMP signaling, exhibiting an EC50 of ≤1 μM. It serves as a valuable chemical probe for BMP signaling analysis, owing to its ability to penetrate zebrafish embryos.
Targets&IC50
BMP:≤1 µM (EC50)
Chemical Properties
Molecular Weight296.72
FormulaC14H14ClFN2O2
Cas No.945189-68-4
SmilesCC(C)Cc1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (303.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3702 mL16.8509 mL33.7018 mL168.5090 mL
5 mM0.6740 mL3.3702 mL6.7404 mL33.7018 mL
10 mM0.3370 mL1.6851 mL3.3702 mL16.8509 mL
20 mM0.1685 mL0.8425 mL1.6851 mL8.4255 mL
50 mM0.0674 mL0.3370 mL0.6740 mL3.3702 mL
100 mM0.0337 mL0.1685 mL0.3370 mL1.6851 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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