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SpdSyn binder-1

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Catalog No. T74696Cas No. 251106-30-6

SpdSyn binder-1 is a weak binding agent that binds to the active site of Plasmodium falciparum spermidine synthase, offering partial inhibition of malaria and potential for malaria research.

SpdSyn binder-1

SpdSyn binder-1

🥰Excellent
Purity: 99.5%
Catalog No. T74696Cas No. 251106-30-6
SpdSyn binder-1 is a weak binding agent that binds to the active site of Plasmodium falciparum spermidine synthase, offering partial inhibition of malaria and potential for malaria research.
Pack SizePriceAvailabilityQuantity
5 mg$64In Stock
10 mg$97In Stock
25 mg$162In Stock
50 mg$238In Stock
100 mg$358In Stock
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Purity:99.5%
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Product Introduction

Bioactivity
Description
SpdSyn binder-1 is a weak binding agent that binds to the active site of Plasmodium falciparum spermidine synthase, offering partial inhibition of malaria and potential for malaria research.
Chemical Properties
Molecular Weight346.43
FormulaC21H22N4O
Cas No.251106-30-6
SmilesC(=O)(C=1C=C2C(=CC1)N=CN2)N3CCN(C/C=C/C4=CC=CC=C4)CC3
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 34.64 mg/mL (100 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8866 mL14.4329 mL28.8659 mL144.3293 mL
5 mM0.5773 mL2.8866 mL5.7732 mL28.8659 mL
10 mM0.2887 mL1.4433 mL2.8866 mL14.4329 mL
20 mM0.1443 mL0.7216 mL1.4433 mL7.2165 mL
50 mM0.0577 mL0.2887 mL0.5773 mL2.8866 mL
100 mM0.0289 mL0.1443 mL0.2887 mL1.4433 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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