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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $45 | In Stock | |
25 mg | $90 | In Stock | |
50 mg | $144 | In Stock | |
100 mg | $225 | In Stock | |
1 mL x 10 mM (in DMSO) | $51 | In Stock |
Description | STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research. |
In vitro | In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels |
Alias | C-170 |
Molecular Weight | 288.3 |
Formula | C15H16N2O4 |
Cas No. | 346691-38-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 22.5 mg/mL (78.04 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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