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Sulotroban

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Catalog No. T68022Cas No. 72131-33-0

sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.

Sulotroban

Sulotroban

🥰Excellent
Purity: 99.29%
Catalog No. T68022Cas No. 72131-33-0
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
Pack SizePriceAvailabilityQuantity
1 mg$90In Stock
5 mg$210In Stock
10 mg$310In Stock
25 mg$586In Stock
50 mg$790In Stock
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Purity:99.29%
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Product Introduction

Bioactivity
Description
sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.
In vivo
Sulotroban (5 mg/kg; i.v.; cat;) did not alter baseline vascular pressures in the cat and responses to the PG and TXA2/PGH2 precursor, arachidonic acid, were reduced. The present data show that sulotroban selectively blocks TXA2/PGH2 receptor-mediated responses in a competitive and reversible manner in the pulmonary vascular bed.[4]
Chemical Properties
Molecular Weight335.37
FormulaC16H17NO5S
Cas No.72131-33-0
SmilesC(CNS(=O)(=O)C1=CC=CC=C1)C2=CC=C(OCC(O)=O)C=C2
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (149.09 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9818 mL14.9089 mL29.8178 mL149.0891 mL
5 mM0.5964 mL2.9818 mL5.9636 mL29.8178 mL
10 mM0.2982 mL1.4909 mL2.9818 mL14.9089 mL
20 mM0.1491 mL0.7454 mL1.4909 mL7.4545 mL
50 mM0.0596 mL0.2982 mL0.5964 mL2.9818 mL
100 mM0.0298 mL0.1491 mL0.2982 mL1.4909 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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