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PI3Kδ-IN-3

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Purity:98.43%

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COA HNMR HPLC

PI3Kδ-IN-3

Catalog No. T26252Cas No. 1431540-99-6

PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.

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Pack Size	Price	Availability
1 mg	$86	In Stock
5 mg	$195	In Stock
10 mg	$311	In Stock
25 mg	$529	In Stock
50 mg	$765	In Stock
100 mg	$1,070	In Stock
500 mg	$2,150	In Stock

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Product Introduction

Bioactivity

Description	PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.
Alias	TC KHNS 11

Chemical Properties

Molecular Weight	492.53
Formula	C28H24N6O3
Cas No.	1431540-99-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (101.52 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0303 mL	10.1517 mL	20.3033 mL	101.5167 mL
5 mM	0.4061 mL	2.0303 mL	4.0607 mL	20.3033 mL
10 mM	0.2030 mL	1.0152 mL	2.0303 mL	10.1517 mL
20 mM	0.1015 mL	0.5076 mL	1.0152 mL	5.0758 mL
50 mM	0.0406 mL	0.2030 mL	0.4061 mL	2.0303 mL
100 mM	0.0203 mL	0.1015 mL	0.2030 mL	1.0152 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc