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Telomerase-IN-2

🥰Excellent
Catalog No. T13115Cas No. 1610878-54-0
Alias Telomerase inhibitor 2

Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).

Telomerase-IN-2

Telomerase-IN-2

🥰Excellent
Purity: 99.32%
Catalog No. T13115Alias Telomerase inhibitor 2Cas No. 1610878-54-0
Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).
Pack SizePriceAvailabilityQuantity
1 mg$135In Stock
5 mg$336In Stock
10 mg$493In Stock
25 mg$892In Stock
50 mg$1,330In Stock
1 mL x 10 mM (in DMSO)$469In Stock
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Purity:99.32%
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Product Introduction

Bioactivity
Description
Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).
Targets&IC50
Telomerase:0.89 µM
In vitro
Telomerase-IN-2 exhibits high activity against Hela, SMMC-7721, SGC-7901, U87 and HepG2 cell lines in the anticancer activity assay in vitro[1].
AliasTelomerase inhibitor 2
Chemical Properties
Molecular Weight633.69
FormulaC34H39N3O9
Cas No.1610878-54-0
SmilesCOc1cc(OC)c2c(c1)oc(-c1cc(OC)c(OC)c(OC)c1)c(OCCCCN1CCN(CC1)C(=O)c1ccncc1)c2=O
Relative Density.1.32 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 235 mg/mL (370.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5781 mL7.8903 mL15.7806 mL78.9029 mL
5 mM0.3156 mL1.5781 mL3.1561 mL15.7806 mL
10 mM0.1578 mL0.7890 mL1.5781 mL7.8903 mL
20 mM0.0789 mL0.3945 mL0.7890 mL3.9451 mL
50 mM0.0316 mL0.1578 mL0.3156 mL1.5781 mL
100 mM0.0158 mL0.0789 mL0.1578 mL0.7890 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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