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TFAP

TFAP
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Purity:100%
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TFAP

Catalog No. T4643Cas No. 1011244-68-0
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor
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Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$72In Stock
10 mg$113In Stock
25 mg$218In Stock
50 mg$396In Stock
100 mg$589In Stock
1 mL x 10 mM (in DMSO)$76In Stock
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Product Introduction

Bioactivity
Description
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor
In vitro
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM, while that against COX-2 is over 200 μM.
AliasN-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Chemical Properties
Molecular Weight281.23
FormulaC13H10F3N3O
Cas No.1011244-68-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (177.79 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5558 mL17.7790 mL35.5581 mL177.7904 mL
5 mM0.7112 mL3.5558 mL7.1116 mL35.5581 mL
10 mM0.3556 mL1.7779 mL3.5558 mL17.7790 mL
20 mM0.1778 mL0.8890 mL1.7779 mL8.8895 mL
50 mM0.0711 mL0.3556 mL0.7112 mL3.5558 mL
100 mM0.0356 mL0.1778 mL0.3556 mL1.7779 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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