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Ubiquitin Isopeptidase Inhibitor I, G5
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Catalog No. T17192Cas No. 108477-18-5
Alias NSC144303
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
Ubiquitin Isopeptidase Inhibitor I, G5
😃Good
Catalog No. T17192Alias NSC144303Cas No. 108477-18-5
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $74 | 6-8 weeks | |
| 10 mg | $128 | 6-8 weeks | |
| 25 mg | $217 | 6-8 weeks | |
| 50 mg | $319 | 6-8 weeks | |
| 100 mg | $478 | 6-8 weeks | |
| 500 mg | $1,090 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively). |
| Targets&IC50 | E1A cells:1.76 μM, E1A/C9DN cells:1.6 μM |
| In vitro | Ubiquitin Isopeptidase Inhibitor I, G5 is a more effective apoptosis inducer, with IC50 values of 1.76 μmol/L and 1.6 μmol/L in E1A and E1A/C9DN cells, respectively[1]. |
| Alias | NSC144303 |
| Molecular Weight | 414.39 |
| Formula | C19H14N2O7S |
| Cas No. | 108477-18-5 |
| Smiles | [O-][N+](=O)c1ccc(\C=C2/CS(=O)(=O)C\C(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)cc1 |
| Relative Density. | 1.541 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (48.26 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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