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Ureidopropionic acid

Ureidopropionic acid
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Ureidopropionic acid

Catalog No. T4919Cas No. 462-88-4
Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in uracil metabolism, produced from dihydrouracil by the enzyme dihydropyrimidase and further decomposed to beta-alanine by beta-ureidopropionase. It is a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with severe toxicity to the antineoplastic agent 5-fluorouracil.
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Pack SizePriceAvailabilityQuantity
50 mg$48In Stock
100 mg$72In Stock
200 mg$98In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Product Introduction

Bioactivity
Description
Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in uracil metabolism, produced from dihydrouracil by the enzyme dihydropyrimidase and further decomposed to beta-alanine by beta-ureidopropionase. It is a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with severe toxicity to the antineoplastic agent 5-fluorouracil.
AliasCarbamoyl-b-alanine, 3-Ureidopropionic acid
Chemical Properties
Molecular Weight132.12
FormulaC4H8N2O3
Cas No.462-88-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (454.14 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.5689 mL37.8444 mL75.6888 mL378.4438 mL
5 mM1.5138 mL7.5689 mL15.1378 mL75.6888 mL
10 mM0.7569 mL3.7844 mL7.5689 mL37.8444 mL
20 mM0.3784 mL1.8922 mL3.7844 mL18.9222 mL
50 mM0.1514 mL0.7569 mL1.5138 mL7.5689 mL
100 mM0.0757 mL0.3784 mL0.7569 mL3.7844 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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