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VU6036720

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Catalog No. T73267

VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probability and single-channel current amplitude.

VU6036720

VU6036720

🥰Excellent
Purity: 97.91%
Catalog No. T73267
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probability and single-channel current amplitude.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$113In Stock
10 mg$197In Stock
25 mg$332In Stock
50 mg$496In Stock
100 mg$693In Stock
500 mg$1,450In Stock
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Purity:97.91%
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Product Introduction

Bioactivity
Description
VU6036720 is a potent and selective inhibitor of the isomeric Kir4.1/5.1.VU6036720 inhibits Kir4.1/5.1 activity by decreasing the channel open-circuit probability and single-channel current amplitude.
In vitro
VU6036720 inhibits Kir4.1/5.1 activity through a reduction of channel open-state probability and single-channel current amplitude (IC50=0.24 μM).[1]
Chemical Properties
Molecular Weight436.93
FormulaC20H22ClFN4O2S
SmilesN#CC1=CC=CC=C1N2C[C@H](C)N(CCNS(=O)(C3=CC=C(F)C(Cl)=C3)=O)CC2
Relative Density.no data available
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (102.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2887 mL11.4435 mL22.8870 mL114.4348 mL
5 mM0.4577 mL2.2887 mL4.5774 mL22.8870 mL
10 mM0.2289 mL1.1443 mL2.2887 mL11.4435 mL
20 mM0.1144 mL0.5722 mL1.1443 mL5.7217 mL
50 mM0.0458 mL0.2289 mL0.4577 mL2.2887 mL
100 mM0.0229 mL0.1144 mL0.2289 mL1.1443 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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