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Zeylenone
Catalog No. TN2328Cas No. 193410-84-3
Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing apoptosis through the PI3K/AKT/mTOR and MAPK/ERK signalling pathways.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $598 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $928 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Zeylenone, a cyclohexene oxide from Uvaria grandiflora, has antitumour and antiproliferative activity, inhibiting cervical cancer cell proliferation and inducing apoptosis through the PI3K/AKT/mTOR and MAPK/ERK signalling pathways. |
| In vitro | Zeylenone (zey), a cyclohexene oxide compound, exerted an obvious inhibitory effect on several cancer cell lines and exhibited little cytotoxicity towards normal cells, enabling zey to play a unique role in combination therapy.we found that zey potentiated the anti-osteosarcoma efficacy of cisplatin and exhibited synergistic interactions with cisplatin in vitro, which also were confirmed in vivo by using xenograft model[1]. |
| Molecular Weight | 382.36 |
| Formula | C21H18O7 |
| Cas No. | 193410-84-3 |
| Storage | keep away from moisture,keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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