(-)-Indolactam V

Name: (-)-Indolactam V
Brand: TargetMol
SKU: T17299
Price: 133 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T17299Cas No. 90365-57-4

Alias Indolactam V

(-)-Indolactam V, a potent PKC activator, exhibits binding affinities (Kis) of 3.36 nM and 1.03 μM for η-CRD2 and γ-CRD2, respectively, and dissociation constants (Kds) of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), and 213 nM (γ-C1B), also demonstrating antitumor activity.

(-)-Indolactam V

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Catalog No. T17299Alias Indolactam VCas No. 90365-57-4

Pack Size	Price	Availability	Quantity
500 μg	$395	35 days
1 mg	$748	35 days

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Product Introduction

Bioactivity

Description	(-)-Indolactam V, a potent PKC activator, exhibits binding affinities (Kis) of 3.36 nM and 1.03 μM for η-CRD2 and γ-CRD2, respectively, and dissociation constants (Kds) of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), and 213 nM (γ-C1B), also demonstrating antitumor activity.
Targets&IC50	PKCγ-C1A:138 nM （kd）, PKCη-C1B:5.5 nM （kd）, PKCβ-C1B:137 nM （kd）, PKCη-CRD2:3.36 nM （ki）, PKCε-C1B:7.7 nM （kd）, PKCθ-C1B:8.7 nM （kd）, PKCδ-C1B:8.3 nM （kd）, PKCγ-C1B:213 nM （kd）, PKCβ-C1A-long:18.9 nM （kd）, PKCδ-C1A:1900 nM （kd）, PKCγ-CRD2:1030 nM （ki）, PKCα-C1A-long:20.8 nM （kd）, PKCα-C1B-long:4000 nM （kd）, PKCε-C1A:4110 nM （kd）, PKCη-C1A:3770 nM （kd）
Alias	Indolactam V

Chemical Properties

Molecular Weight	301.38
Formula	C₁₇H₂₃N₃O₂
Cas No.	90365-57-4
Relative Density.	1.31g/cm3

Storage & Solubility Information

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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