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(R)-Elagolix

(R)-Elagolix
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
Catalog No. T11174Cas No. 834153-87-6
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Purity:97.63%
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(R)-Elagolix

Catalog No. T11174Cas No. 834153-87-6
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$32In Stock
2 mg$45In Stock
5 mg$72In Stock
10 mg$113In Stock
25 mg$198In Stock
50 mg$347In Stock
100 mg$513In Stock
200 mg$732In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Product Introduction

Bioactivity
Description
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
Targets&IC50
GnRHR: Ki : 3.7 nM, GnRHR:0.25 nM
AliasNBI-56418
Chemical Properties
Molecular Weight631.59
FormulaC32H30F5N3O5
Cas No.834153-87-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (158.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5833 mL7.9165 mL15.8331 mL79.1653 mL
5 mM0.3167 mL1.5833 mL3.1666 mL15.8331 mL
10 mM0.1583 mL0.7917 mL1.5833 mL7.9165 mL
20 mM0.0792 mL0.3958 mL0.7917 mL3.9583 mL
50 mM0.0317 mL0.1583 mL0.3167 mL1.5833 mL
100 mM0.0158 mL0.0792 mL0.1583 mL0.7917 mL

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