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(S)-Flurbiprofen

🥰Excellent
Catalog No. T5843LCas No. 51543-39-6
Alias esflurbiprofen

Esflurbiprofen is an inhibitor of COX-1 and COX-2.

(S)-Flurbiprofen

(S)-Flurbiprofen

🥰Excellent
Purity: 99.88%
Catalog No. T5843LAlias esflurbiprofenCas No. 51543-39-6
Esflurbiprofen is an inhibitor of COX-1 and COX-2.
Pack SizePriceAvailabilityQuantity
10 mg$29In Stock
50 mgInquiryIn Stock
1 mL x 10 mM (in DMSO)$41In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
Esflurbiprofen is an inhibitor of COX-1 and COX-2.
Targets&IC50
COX-1:0.48 μM, COX-2:0.47 μM
In vitro
(S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin.
Aliasesflurbiprofen
Chemical Properties
Molecular Weight244.26
FormulaC15H13FO2
Cas No.51543-39-6
SmilesC[C@H](C(O)=O)c1ccc(c(F)c1)-c1ccccc1
Relative Density.1.199 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 95 mg/mL (388.93 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0940 mL20.4700 mL40.9400 mL204.6999 mL
5 mM0.8188 mL4.0940 mL8.1880 mL40.9400 mL
10 mM0.4094 mL2.0470 mL4.0940 mL20.4700 mL
20 mM0.2047 mL1.0235 mL2.0470 mL10.2350 mL
50 mM0.0819 mL0.4094 mL0.8188 mL4.0940 mL
100 mM0.0409 mL0.2047 mL0.4094 mL2.0470 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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