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α-Tocopherol phosphate disodium

Catalog No. T63918 CAS 60934-46-5

Synonyms: TocP disodium, Vitamin E phosphate disodium

α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium impedes endothelial progenitor cell apoptosis, enhances endothelial progenitor cell migration under high glucose/low oxygen conditions and promotes angiogenesis. α-Tocopherol phosphate disodium prevents apoptosis, enhances migration of endothelial progenitor cells under high glucose/low oxygen conditions and promotes angiogenesis.

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α-Tocopherol phosphate disodium, CAS 60934-46-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	TocP disodium, Vitamin E phosphate disodium
Molecular Weight	554.659
Formula	C29H49Na2O5P
CAS No.	60934-46-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 4.1 mg/mL (7.4 mM), ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11(1):22400. 2. Wu Z, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018 Apr;67(4):1263-1273.e1.

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Keywords

α-Tocopherol phosphate disodium 60934-46-5 Apoptosis Immunology/Inflammation Metabolism NF-Κb oxidation-reduction Antioxidant Reactive Oxygen Species Vitamin E phosphate disodium TocP disodium Inhibitor inhibitor inhibit

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