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10-Gingerol

Catalog No. T3908 CAS 23513-15-7

10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).

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10-Gingerol, CAS 23513-15-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 34.00
5 mg	In stock	$ 72.00
10 mg	In stock	$ 98.00
25 mg	In stock	$ 168.00
50 mg	In stock	$ 249.00
1 mL * 10 mM (in DMSO)	In stock	$ 56.00

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Purity: 99.17%

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Description	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).
Source	Natural Products > Zingiberaceae > Zingiber

Molecular Weight	350.49
Formula	C21H34O4
CAS No.	23513-15-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 64 mg/mL(182.6 mM)

References and Literature

1. Ryu MJ1, Chung HS.[10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.In Vitro Cell Dev Biol Anim. 2015 Jan;51(1):92-101. 2. Ho SC1, Chang KS, Lin CC.Anti-neuroinflammatory capacity of fresh ginger is attributed mainly to 10-gingerol.Food Chem. 2013 Dec 1;141(3):3183-91. 3. Sadakane C1, Muto S, Nakagawa K,et al.10-Gingerol, a component of rikkunshito, improves cisplatin-induced anorexia by inhibiting acylated ghrelin degradation.Biochem Biophys Res Commun. 2011 Sep 2;412(3):506-11.

Citations

1. Zhang B, Zhao J, Wang Z, et al. Identification of Multi-Target Anti-AD Chemical Constituents From Traditional Chinese Medicine Formulae by Integrating Virtual Screening and In Vitro Validation. Frontiers in Pharmacology. 2021：1781

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Anti-COVID-19 Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library Anti-Aging Compound Library Apoptosis Compound Library Selected Plant-Sourced Compound Library Anti-Tumor Natural Product Library NO PAINS Compound Library HIF-1 Signaling Pathway Compound Library Antioxidant Compound Library

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Keywords

10-Gingerol 23513-15-7 Apoptosis Inhibitor 10Gingerol 10 Gingerol inhibit inhibitor

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